Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 3/20 | 0.50 |
| ▸ | CDK4 | P11802 | 3/20 | 0.50 |
| ▸ | CCND1 | P24385 | 3/20 | 0.50 |
| ▸ | HTR1D | P28221 | 12/20 | 0.47 |
| ▸ | HTR1B | P28222 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866630 | 0.78 | MPO (0.64) | HTR1FCDK4CCND1HTR1DHTR1B | |
| SCHEMBL7860323 | 0.78 | MMP2 (0.49) | HTR1FHTR1DHTR1BHTR1ACHRM2 | |
| SCHEMBL1998690 | 0.77 | HPGD (0.54) | HTR1FCDK4CCND1HTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL8194413 | 0.76 | HTR1F (0.47) | HTR1FCDK4CCND1HTR1DHTR1B | |
| SCHEMBL7867834 | 0.74 | NQO2 (0.56) | HTR1DHTR1BHTR1AMAPT | |
| SCHEMBL7866613 | 0.73 | HTR1D (0.47) | HTR1FHTR1DHTR1BHTR1AMAPT | |
| SCHEMBL4397592 | 0.72 | IDO1 (0.51) | CDK4CCND1MPO | |
| SCHEMBL10580738 | 0.71 | MTNR1A (0.46) | CDK4CCND1HTR1DHTR1BHTR1A | |
| SCHEMBL9256341 | 0.70 | MPO (0.53) | HTR1DMAPTMPO | |
| SCHEMBL4391535 | 0.70 | CDK4 (0.51) | CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083918-A1 | NOVEL THERAPEUTIC AGENTS THAT MODULATE 5-HT RECEPTORS | Advanced Medicine, Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999064044-A1 | NOVEL THERAPEUTIC AGENTS THAT MODULATE 5-HT RECEPTORS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |