Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5564719 | 0.98 | HPGD (0.66) | HPGDGAAMEN1KMT2ACYP2C9 | |
| SCHEMBL12018338 | 0.91 | CES2 (0.56) | HPGDGAAMEN1KMT2ACYP2C9 | |
| SCHEMBL28916549 | 0.89 | HPGD (0.69) | HPGDMEN1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL29738490 | 0.83 | HPGD (0.58) | HPGDGAAMEN1KMT2ACYP2C9 | |
| SCHEMBL8386522 | 0.82 | PHGDH (0.70) | HPGDGAAMEN1KMT2ACYP2C9 | |
| SCHEMBL7837595 | 0.82 | SIGMAR1 (0.68) | HPGDUSP2ALDH1A1CES2CES1 | |
| SCHEMBL8566690 | 0.82 | HPGD (0.62) | HPGDGAAKMT2ACYP2C9POLB | |
| Water SCHEMBL27661765 | 0.81 | PHGDH (0.68) | HPGDGAAMEN1KMT2ACYP2C9 | |
| SCHEMBL28919752 | 0.81 | MAPT (0.63) | MEN1KMT2ACYP2C9ALOX5USP2 | |
| SCHEMBL23564897 | 0.80 | HPGD (0.58) | HPGDGAAMEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504946-B | Method for synthesizing alpha-ketoamide compound | 武汉工程大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115504946-A | Method for synthesizing alpha-keto amide compound | 武汉工程大学 | 2022-12-23 | — | — | CN | disclosed |
| CN-113248458-B | Preparation method of alpha-carbonyl amide compound | 陕西省煤田地质集团有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113248458-A | Preparation method of alpha-carbonyl amide compound | 陕西省煤田地质集团有限公司 | 2021-08-13 | — | — | CN | disclosed |
| WO-2011082077-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-07-07 | — | — | WO | disclosed |