Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987543 | 0.81 | MAOB (0.43) | FFAR4FFAR1CD274 | |
| SCHEMBL19987563 | 0.76 | MRGPRX4 (0.44) | MRGPRX4FFAR4FFAR1 | |
| SCHEMBL19987586 | 0.70 | MRGPRX4 (0.38) | MRGPRX4FFAR4FFAR1 | |
| SCHEMBL18831377 | 0.70 | MRGPRX4 (0.33) | MRGPRX4 | |
| SCHEMBL19987565 | 0.70 | ELANE (0.35) | — | |
| SCHEMBL18831644 | 0.67 | MRGPRX4 (0.33) | MRGPRX4BRD4 | |
| SCHEMBL19987597 | 0.67 | SMN1; SMN2 (0.43) | MRGPRX4FFAR4FFAR1CD274 | |
| SCHEMBL18831378 | 0.67 | — | — | |
| SCHEMBL19987585 | 0.66 | HPGD (0.35) | MRGPRX4CD274 | |
| SCHEMBL19987547 | 0.66 | HPGD (0.35) | MRGPRX4PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |