Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20742253 | 0.84 | TUBB1 (0.44) | MAOBMAOANPC1RAB9AERN1 | |
| SCHEMBL865350 | 0.81 | MAOA (0.58) | MAOBMAOANPC1RAB9AERN1 | |
| SCHEMBL19810818 | 0.81 | ALDH1A1 (0.49) | ERN1ALDH1A1CYP1A2CYP2C9L3MBTL1 | |
| SCHEMBL14572745 | 0.81 | PTPN1 (0.47) | MAOBALDH1A1PTPN1L3MBTL1CASP3 | |
| SCHEMBL435043 | 0.80 | ALDH1A1 (0.61) | MAOBMAOANPC1RAB9AERN1 | |
| SCHEMBL2901494 | 0.80 | PPARG (0.45) | MAOBMAOANPC1RAB9ACYP3A4 | |
| SCHEMBL2901054 | 0.80 | MAOB (0.47) | MAOBMAOANPC1RAB9ACYP3A4 | |
| SCHEMBL3370062 | 0.79 | MAOB (0.52) | MAOBMAOANPC1RAB9AERN1 | |
| SCHEMBL6836250 | 0.78 | PPARG (0.55) | MAOBMAOAERN1POLBMAPT | |
| SCHEMBL1855277 | 0.78 | MAOB (0.55) | MAOBMAOANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107868091-B | Meddigesin, derivatives thereof and preparation method thereof | 怀特生技新药股份有限公司 | 2020-08-28 | — | — | CN | disclosed |
| US-10385061-B2 | Medicarpin, its derivatives, manufacturing method thereof | PHYTOHEALTH CORPORATION (TW) | 2019-08-20 | — | — | US | disclosed |
| US-10385061-B2 | Medicarpin, its derivatives, manufacturing method thereof | PHYTOHEALTH CORPORATION (TW) | 2019-08-20 | — | — | US | disclosed |
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PHYTOHEALTH CORPORATION (TW) | 2018-03-29 | — | — | US | disclosed |
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PHYTOHEALTH CORPORATION (TW) | 2018-03-29 | — | — | US | disclosed |
| EP-3299373-A2 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | PhytoHealth Corporation (TW) | 2018-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086772-A1 | MEDICARPIN, ITS DERIVATIVES, MANUFACTURING METHOD THEREOF | SHARPIN, TIPARP, MYADM | MAOB 1213/4885MAOA 1263/4885NPC1 3703/4885 |
| US-10385061-B2 | Medicarpin, its derivatives, manufacturing method thereof | SHARPIN, ATP6V1B1, REN | MAOB 1618/4885MAOA 2027/4885NPC1 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.