Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 3/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757861 | 0.87 | MAPT (0.53) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4426068 | 0.86 | NOTUM (0.64) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6990234 | 0.86 | ALDH1A1 (0.60) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6425207 | 0.82 | KMT2A (0.52) | KCNJ1KMT2AALDH1A1RAB9ATP53 | |
| SCHEMBL6994169 | 0.82 | KCNJ1 (0.50) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6990316 | 0.81 | KCNJ1 (0.49) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6990901 | 0.80 | KCNJ1 (0.48) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4414155 | 0.79 | KMT2A (0.50) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL28476725 | 0.79 | RAB9A (0.46) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A | |
| SCHEMBL1072252 | 0.79 | KCNJ1 (0.71) | KCNJ1NOTUMMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10279334-B2 | Microporous metal-organic frameworks for the removal of acetylene from ethylene | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-05-07 | — | — | US | disclosed |
| US-20180085733-A1 | MICROPOROUS METAL-ORGANIC FRAMEWORKS FOR THE REMOVAL OF ACETYLENE FROM ETHYLENE | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085733-A1 | MICROPOROUS METAL-ORGANIC FRAMEWORKS FOR THE REMOVAL OF ACETYLENE FROM ETHYLENE | AOC1, AOC2, SOD1 | KCNJ1 1995/4885NOTUM 2379/4885MAPT 1926/4885 |
| US-10279334-B2 | Microporous metal-organic frameworks for the removal of acetylene from ethylene | AOC1, AOC2, SOD1 | KCNJ1 1995/4885NOTUM 2379/4885MAPT 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.