Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24747257 | 0.85 | LOXL2 (0.38) | LOXL2KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL22882333 | 0.83 | KLKB1 (0.39) | LOXL2KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL506900 | 0.83 | LOXL2 (0.37) | LOXL2KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL1585868 | 0.79 | KDM1A (0.44) | LOXL2KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL5427126 | 0.79 | SLC6A4 (0.49) | LOXL2HTR7SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15308657 | 0.78 | TRPA1 (0.40) | MAPTALDH1A1TAAR1NOS1NOS3 | |
| SCHEMBL16812425 | 0.76 | HTR7 (0.46) | LOXL2KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL15699681 | 0.76 | LOXL2 (0.37) | LOXL2KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL2236823 | 0.75 | NCF1 (0.61) | KDM4EPRMT6ALDH1A1NCF1 | |
| SCHEMBL8281938 | 0.74 | ALDH1A1 (0.45) | LOXL2KDM4ECYP3A4MAPTPRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |