Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
| ▸ | SNCA | P37840 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993339 | 0.79 | SNCA (0.35) | LOXL2SNCA | |
| SCHEMBL19993467 | 0.76 | MAOB (0.30) | — | |
| SCHEMBL22621241 | 0.76 | — | — | |
| SCHEMBL22621129 | 0.74 | DYRK1A (0.30) | — | |
| SCHEMBL19993380 | 0.73 | RXRA (0.40) | CYP19A1CYP11B1CYP11B2RXRARXRB | |
| SCHEMBL19993402 | 0.72 | CYP17A1 (0.41) | CYP19A1ESR2CYP11B1CYP11B2 | |
| SCHEMBL19993381 | 0.70 | SAE1 (0.39) | CYP19A1LOXL2CYP11B1CYP11B2SAE1 | |
| SCHEMBL19993340 | 0.70 | AR (0.32) | — | |
| SCHEMBL19993389 | 0.68 | LOXL2 (0.38) | LOXL2CYP11B2SAE1UBA2 | |
| SCHEMBL19993382 | 0.67 | LOXL2 (0.43) | CYP19A1LOXL2CYP11B1CYP11B2SAE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512920-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| WO-2018050573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |