Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.30 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993467 | 0.83 | MAOB (0.30) | MAOBTRPV4 | |
| SCHEMBL19993384 | 0.79 | CYP19A1 (0.33) | SNCALOXL2 | |
| SCHEMBL22621129 | 0.75 | DYRK1A (0.30) | — | |
| SCHEMBL19993390 | 0.74 | CYP17A1 (0.32) | — | |
| SCHEMBL22621241 | 0.73 | — | — | |
| SCHEMBL19993382 | 0.71 | LOXL2 (0.43) | LOXL2 | |
| SCHEMBL19993336 | 0.71 | — | — | |
| SCHEMBL15393729 | 0.69 | MAOB (0.47) | SNCALOXL2MAOBMAOATRPV4 | |
| SCHEMBL19993380 | 0.67 | RXRA (0.40) | SNCA | |
| SCHEMBL22621190 | 0.67 | GPR3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512920-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| WO-2018050573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |