Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 4/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29966805 | 1.00 | TDP1 (0.57) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL12066584 | 0.88 | TDP1 (0.52) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL9811597 | 0.80 | ALDH1A1 (0.59) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL4647699 | 0.80 | TDP1 (0.55) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL57954 | 0.79 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL30616278 | 0.79 | TDP1 (0.48) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL25355019 | 0.78 | TTR (0.49) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL8091607 | 0.78 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL2078816 | 0.78 | TTR (0.57) | TDP1ATMALDH1A1HIF1ATTR | |
| SCHEMBL17680657 | 0.78 | TDP1 (0.44) | TDP1ATMALDH1A1HIF1ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646199-B | The preparation technology of the trifluoro-benzoic acid of 3 chlorine 2,4,5 | 连云港威远精细化工有限公司 | 2017-10-03 | — | — | CN | claimed |
| WO-2015160562-A1 | SULFONATION OF AROMATIC POLYMERS IN THE PRESENCE OF A POLYFLUORINATED BENZENE COMPOUND AS SWELLING AGENT | ROHM AND HAAS COMPANY (US) | 2015-10-22 | — | — | WO | claimed |
| US-8952083-B2 | Fluorocopolymer composition and its production process | ASAHI GLASS COMPANY, LIMITED (JP) | 2015-02-10 | — | — | US | claimed |
| EP-4673141-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | Sionna Therapeutics Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| WO-2025031468-A1 | HETEROARYL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2025-02-13 | — | — | WO | disclosed |
| CN-118930547-A | Ureido-substituted fused heteroaryl compounds, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118684675-A | Amide substituted pyrazoloheteroaryl compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| EP-3928836-B1 | N-SUBSTITUTED INDOLE DERIVATIVES AS PGE2 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-09-18 | — | — | EP | disclosed |
| WO-2024182751-A1 | NBD1 MODULATORS AND METHODS OF USING THE SAME | SIONNA THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| CN-118515674-A | Amide compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-08-20 | — | — | CN | disclosed |
| US-12011444-B2 | N-substituted indole derivatives as PGE2 receptor modulators | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-06-18 | — | — | US | disclosed |
| EP-2338935-A1 | FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF | ASAHI GLASS COMPANY, LIMITED (JP) | 2011-06-29 | — | — | EP | disclosed |
| US-7094900-B2 | N-Aryl-2-oxazolidinones and their derivatives | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-22 | — | — | US | disclosed |
| EP-1539745-B1 | N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES | PHARMACIA & UPJOHN CO LLC (US) | 2006-03-29 | — | — | EP | disclosed |
| EP-1539745-A1 | N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20040072873-A1 | N-Aryl-2-oxazolidinones and their derivatives | GADWOOD ROBERT C (US) | 2004-04-15 | — | — | US | disclosed |
| WO-2004014897-A1 | N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-0596130-B1 | PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE | SDS BIOTECH CORP (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0596130-A1 | PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE | SDS Biotech K.K. (JP) | 1994-05-11 | — | — | EP | disclosed |
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12011444-B2 | N-substituted indole derivatives as PGE2 receptor modulators | PTGER1, PTGER4, PTGER2 | TDP1 3691/4885ATM 3858/4885ALDH1A1 761/4885 |
| US-20040072873-A1 | N-Aryl-2-oxazolidinones and their derivatives | OXA1L, NDUFS7, NDUFS6 | TDP1 4591/4885ATM 3984/4885ALDH1A1 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.