Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121687 | 0.89 | ACSS2 (0.34) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL19993433 | 0.89 | ACSS2 (0.34) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL19993460 | 0.83 | LMNA (0.34) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL19993247 | 0.82 | HTR6 (0.35) | KCNH2CNR2NPC1RAB9APTGS2 | |
| SCHEMBL21265226 | 0.82 | POLB (0.41) | RORCS1PR1 | |
| SCHEMBL19993257 | 0.81 | S1PR1 (0.40) | KCNH2RORCCNR2NPC1RAB9A | |
| SCHEMBL21264906 | 0.81 | JAK2 (0.37) | KCNH2RORC | |
| SCHEMBL19993258 | 0.81 | RORC (0.35) | KCNH2RORCCNR2LMNAHTT | |
| SCHEMBL30130684 | 0.79 | KCNH2 (0.33) | KCNH2RORCCNR2 | |
| SCHEMBL19973846 | 0.77 | HTR6 (0.37) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515921-B1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-10611779-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-04-07 | — | — | US | disclosed |
| US-20190248811-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-15 | — | — | US | disclosed |
| WO-2018050825-A1 | PYRAZOLO [1,5-A]PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10611779-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, BCHE, ACHE | KCNH2 872/4885RORC 3144/4885CNR2 698/4885 |
| US-20190248811-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, BCHE, ACHE | KCNH2 872/4885RORC 3144/4885CNR2 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.