SCHEMBL199943

SCHEMBL199943

CC(C)(C)Sc1cc(-c2ccccc2)c([O])c(-c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 2/20 0.36
BACE1 P56817 2/20 0.34
METAP2 P50579 3/20 0.33
HPRT1 P00492 1/20 0.33
PTPN1 P18031 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PTGS2 P35354 4/20 0.32
PTGS1 P23219 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
FABP2 P12104 1/20 0.32
TSHR P16473 1/20 0.32
AKR1C4 P17516 1/20 0.32
ADRA2B P18089 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2C P28335 1/20 0.32
DRD3 P35462 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL202583 0.82 SLC22A12 (0.35) SLC22A12PTGS2HTR7
SCHEMBL199944 0.81 BACE1 (0.45) SLC22A12BACE1PTPN1ALDH1A1MEN1
SCHEMBL202584 0.77 SOAT1 (0.35)
SCHEMBL2332225 0.75 NPC1 (0.46) BACE1METAP2ALDH1A1
SCHEMBL15509351 0.71 METAP2 (0.55) BACE1METAP2HPRT1ALDH1A1TSHR
SCHEMBL309669 0.71 PTPN1 (0.50) BACE1HPRT1PTPN1ALDH1A1PTGS1
SCHEMBL575613 0.70 HSD17B10 (0.45) ALDH1A1TSHRLMNAMAPTCYP2C9
SCHEMBL199037 0.69 ALDH1A1 (0.43) ALDH1A1PTGS2MAPTHPGDHTR7
Fluoride SCHEMBL777953 0.68 HSD17B10 (0.43) ALDH1A1TSHRLMNAMAPTCYP2C9
Fluoride SCHEMBL1335636 0.68 HSD17B10 (0.43) ALDH1A1TSHRLMNAMAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10230023-B2 Color converter BASF SE (DE) 2019-03-12 US disclosed
EP-2718395-B1 Novel illumination device comprising a colour converter BASF SE (DE) 2018-02-28 EP disclosed
US-20160284947-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2016-09-29 US disclosed
US-9406848-B2 Color converter BASF SE (DE) 2016-08-02 US disclosed
EP-1917311-B1 Rylene based multiple chromophores BASF SE (DE) 2015-09-23 EP disclosed
EP-2718395-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2014-04-16 EP disclosed
US-8501948-B2 Multiple chromophores based on rylene BASF AKTIENGESELLSCHAFT (DE) 2013-08-06 US disclosed
WO-2012168395-A1 NOVEL COLOR CONVERTER BASF SE (DE) 2012-12-13 WO disclosed
US-20120138125-A1 FLUORESCENT SOLAR CONVERSION CELLS BASED ON FLUORESCENT TERYLENE DYES BASF SE (DE) 2012-06-07 US disclosed
US-8088922-B2 Dibenzorylenetetracarboximides as infrared absorbers BASF AKTIENGESELLSCHAFT (DE) 2012-01-03 US disclosed
US-20100048904-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF AKTIENGESELLSCHAFT (DE) 2010-02-25 US disclosed
EP-2029573-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2009-03-04 EP disclosed
US-20080287678-A1 Multiple Chromophores Based on Rylene BASF AKTIENGESELLSCHAFT (DE) 2008-11-20 US disclosed
US-20080245411-A1 Fluorescent Solar Conversion Cells Based on Fluorescent Terylene Dyes BASF SE 2008-10-09 US disclosed
US-20080167467-A1 Substituted Rylene Derivatives BASF AKTIENGESELLSCHAFT (DE) 2008-07-10 US disclosed
EP-1917311-A2 MULTIPLE CHROMOPHORES BASF SE (DE) 2008-05-07 EP disclosed
EP-1904497-A1 SUBSTITUTED RYLENE DERIVATIVES BASF SE (DE) 2008-04-02 EP disclosed
WO-2007138051-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS BASF SE (DE) 2007-12-06 WO disclosed
WO-2007014902-A2 MULTIPLE CHROMOPHORES BASED ON RYLENE BASF SE (DE) 2007-02-08 WO disclosed
WO-2007006717-A1 SUBSTITUTED RYLENE DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2007-01-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167467-A1 Substituted Rylene Derivatives NR3C2, NR2C2, NR2E3 SLC22A12 627/4885BACE1 4387/4885METAP2 2695/4885
US-20100048904-A1 DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS TDO2, C9, CYP3A43 SLC22A12 494/4885BACE1 1904/4885METAP2 1321/4885
US-20080287678-A1 Multiple Chromophores Based on Rylene TDO2, PPOX, NPY1R SLC22A12 642/4885BACE1 4681/4885METAP2 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.