Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.56 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799028 | 0.86 | ACACB (0.46) | ELOVL1LRRK2ACACBHRH4 | |
| SCHEMBL20000634 | 0.79 | ELOVL1 (0.49) | ELOVL1ACACBMAPTSMN1; SMN2HRH4 | |
| SCHEMBL19468728 | 0.78 | ELOVL1 (0.58) | ELOVL1ACACBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8322225 | 0.77 | MAOB (0.58) | AGXTALDH1A1SMN1; SMN2KDM4EALOX12 | |
| SCHEMBL4573250 | 0.76 | CHRM4 (0.54) | ACACBKMT2ACYP2C9NPC1RAB9A | |
| SCHEMBL3103344 | 0.76 | MAOB (0.57) | AGXTALDH1A1SMN1; SMN2KDM4EALOX12 | |
| SCHEMBL19468798 | 0.75 | ELOVL1 (0.55) | ELOVL1ACACBMAPTHRH4CHKA | |
| SCHEMBL20000560 | 0.75 | ELOVL1 (0.61) | ELOVL1ACACBMAPTSMN1; SMN2TP53 | |
| SCHEMBL29068037 | 0.75 | CHRNB2 (0.46) | LRRK2ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL30500456 | 0.75 | CHRNB2 (0.46) | LRRK2ALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997024-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-28 | — | — | EP | disclosed |