Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.54 |
| ▸ | ACACB | O00763 | 7/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113167 | 0.88 | GPR119 (0.54) | CHRM4ACACBFAAHHDAC1 | |
| SCHEMBL4573033 | 0.88 | GPR119 (0.54) | CHRM4ACACBFAAHHDAC1 | |
| SCHEMBL4573864 | 0.84 | CHRM4 (0.57) | CHRM4NPC1FAAHCHRM2CHRM1 | |
| SCHEMBL22411529 | 0.82 | RAB9A (0.53) | CHRM4ACACBNPC1RAB9AFAAH | |
| SCHEMBL21551278 | 0.79 | GPR119 (0.59) | CHRM4CHRM2CHRM1CHRM3 | |
| SCHEMBL4573042 | 0.77 | SLC6A7 (0.45) | CHRM4NPC1RAB9AFAAHKMT2A | |
| SCHEMBL20000616 | 0.76 | ELOVL1 (0.56) | ACACBNPC1RAB9AKMT2ACYP2C9 | |
| SCHEMBL20139213 | 0.75 | FAAH (0.54) | CHRM4NPC1RAB9AFAAHKMT2A | |
| SCHEMBL27606539 | 0.75 | FAAH (0.54) | CHRM4NPC1RAB9AFAAHKMT2A | |
| SCHEMBL26637018 | 0.75 | CTSB (0.37) | CHRM4NPC1RAB9AKMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |