Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | LOX | P28300 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000616 | 0.79 | ELOVL1 (0.56) | ELOVL1ACACBHRH4LTA4HHRH3 | |
| SCHEMBL11510734 | 0.76 | SLC6A2 (0.52) | LTA4HMAPT | |
| SCHEMBL20000561 | 0.76 | CHRNB2 (0.48) | ACACBPLK4LTA4HPTGS2HRH3 | |
| SCHEMBL31221199 | 0.76 | LOXL2 (0.43) | LOXL2LOXACACBPLK4NPC1 | |
| SCHEMBL30228382 | 0.75 | SLC6A2 (0.51) | LTA4HHRH3MAPT | |
| SCHEMBL28087592 | 0.75 | ALDH1A1 (0.47) | LTA4HSMN1; SMN2MAPT | |
| SCHEMBL19468728 | 0.74 | ELOVL1 (0.58) | ELOVL1DRD1ACACBHRH4CHKA | |
| SCHEMBL10672705 | 0.74 | NPC1 (0.63) | LOXL2LOXACACBHRH3NPC1 | |
| SCHEMBL19468840 | 0.73 | ELOVL1 (0.50) | ELOVL1ACACBHRH4CHKA | |
| SCHEMBL30345867 | 0.72 | TSHR (0.55) | HRH4CHKANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997024-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-28 | — | — | EP | disclosed |