Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002434 | 1.00 | L3MBTL1 (0.56) | L3MBTL1HSD11B1MAPTKMT2AALDH1A1 | |
| SCHEMBL20002498 | 0.89 | RORC (0.49) | L3MBTL1MAPTRORCEPHX2 | |
| SCHEMBL20002251 | 0.88 | RORC (0.52) | L3MBTL1ALDH1A1RORCNR1I2 | |
| SCHEMBL20002743 | 0.88 | L3MBTL1 (0.48) | L3MBTL1MAPTALDH1A1RORCNR1I2 | |
| SCHEMBL20002731 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1RORCNR1I2EPHX2 | |
| SCHEMBL20003057 | 0.88 | RORC (0.50) | L3MBTL1MAPTALDH1A1RORCEPHX2 | |
| SCHEMBL20002254 | 0.88 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1RORCNR1I2EPHX2 | |
| SCHEMBL20002920 | 0.87 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL20002684 | 0.86 | L3MBTL1 (0.47) | L3MBTL1MAPTALDH1A1RORCNR1I2 | |
| SCHEMBL20002488 | 0.85 | RORC (0.47) | L3MBTL1MAPTKMT2AALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |