Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002751 | 0.85 | NOTUM (0.42) | NOTUMRORCMAPT | |
| SCHEMBL20002969 | 0.83 | NOTUM (0.45) | ALDH1A1KMT2ANOTUMRORCMAPT | |
| SCHEMBL20002669 | 0.83 | NOTUM (0.45) | ALDH1A1KMT2ANOTUMRORCMAPT | |
| SCHEMBL20002958 | 0.81 | NOTUM (0.48) | ALDH1A1POLBKMT2ANOTUMEPHX2 | |
| SCHEMBL20002957 | 0.81 | NOTUM (0.48) | ALDH1A1POLBKMT2ANOTUMEPHX2 | |
| SCHEMBL20002207 | 0.78 | RORC (0.45) | NOTUMRORCMAPTNPC1 | |
| SCHEMBL20002341 | 0.78 | MAPT (0.48) | ALDH1A1KMT2ANOTUMRORCMAPT | |
| SCHEMBL20002250 | 0.78 | MAPT (0.48) | ALDH1A1KMT2ANOTUMRORCMAPT | |
| SCHEMBL20002773 | 0.76 | RORC (0.44) | ALDH1A1KMT2ANOTUMRORCMAPT | |
| SCHEMBL20002685 | 0.76 | HSD11B1 (0.41) | ALDH1A1RORCMAPTPKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |