Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002561 | 0.89 | RORC (0.50) | RORC | |
| SCHEMBL20002207 | 0.86 | RORC (0.45) | RORC | |
| SCHEMBL20003010 | 0.85 | RORC (0.43) | RORC | |
| SCHEMBL20002976 | 0.83 | RORC (0.43) | RORC | |
| SCHEMBL20003077 | 0.78 | RORC (0.48) | RORC | |
| SCHEMBL20002822 | 0.78 | RORC (0.58) | RORC | |
| SCHEMBL20003110 | 0.77 | RORC (0.41) | RORC | |
| SCHEMBL20003094 | 0.76 | TACR3 (0.33) | RORC | |
| SCHEMBL20002767 | 0.75 | RORC (0.43) | RORC | |
| SCHEMBL20002171 | 0.74 | KMT2A (0.38) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |