Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009414 | 0.63 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL20008150 | 0.61 | RAB9A (0.41) | KMT2A | |
| SCHEMBL26696562 | 0.60 | P2RX7 (0.44) | HSD17B10 | |
| SCHEMBL20009423 | 0.60 | MEN1 (0.36) | HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL20009422 | 0.60 | MEN1 (0.33) | HSD17B10MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL26613227 | 0.59 | P2RX7 (0.43) | HSD17B10 | |
| SCHEMBL18432558 | 0.59 | MEN1 (0.36) | HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL25724196 | 0.58 | MEN1 (0.41) | HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL18568450 | 0.57 | MEN1 (0.53) | MEN1KMT2ATSHR | |
| SCHEMBL25644373 | 0.55 | P2RX7 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |