Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009422 | 0.82 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20008147 | 0.69 | CASP1 (0.35) | — | |
| SCHEMBL20008548 | 0.69 | TP53 (0.31) | — | |
| SCHEMBL20009423 | 0.68 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20008186 | 0.68 | — | — | |
| SCHEMBL20009402 | 0.65 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL18432558 | 0.64 | MEN1 (0.36) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL20008155 | 0.63 | HSD17B10 (0.33) | MEN1KMT2A | |
| SCHEMBL20008495 | 0.61 | MEN1 (0.33) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21507836 | 0.61 | MEN1 (0.35) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |