Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008363 | 0.72 | MAPT (0.37) | — | |
| SCHEMBL20009063 | 0.71 | NPC1 (0.39) | — | |
| SCHEMBL20008150 | 0.69 | RAB9A (0.41) | — | |
| SCHEMBL20008379 | 0.68 | — | — | |
| SCHEMBL20008254 | 0.67 | NPC1 (0.34) | — | |
| SCHEMBL20008361 | 0.62 | KMT2A (0.35) | PABPC1 | |
| SCHEMBL20008164 | 0.62 | MAPT (0.32) | — | |
| SCHEMBL20008487 | 0.61 | NPC1 (0.36) | — | |
| SCHEMBL20009440 | 0.60 | HTT (0.36) | — | |
| SCHEMBL20008308 | 0.60 | NPC1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |