Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 11/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8274248 | 0.87 | GRIN1 (0.56) | GRIN2BGRIN1ALDH1A1L3MBTL1PARP1 | |
| SCHEMBL20171236 | 0.80 | ALDH1A1 (0.50) | GRIN2BGRIN1ALDH1A1L3MBTL1PARP1 | |
| SCHEMBL20049822 | 0.80 | ALDH1A1 (0.51) | GRIN2BGRIN1ALDH1A1L3MBTL1PARP1 | |
| SCHEMBL20008381 | 0.76 | RAF1 (0.45) | GRIN2BGRIN1ATMKDM4E | |
| SCHEMBL15730622 | 0.74 | PDE2A (0.49) | GRIN2BGRIN1ALDH1A1BRD4 | |
| SCHEMBL29134978 | 0.73 | GRIN1 (0.55) | GRIN2BGRIN1ALDH1A1L3MBTL1PARP1 | |
| SCHEMBL15394274 | 0.73 | KIF11 (0.54) | GRIN2BGRIN1ALDH1A1GAAATM | |
| SCHEMBL17132076 | 0.73 | RXRA (0.45) | GRIN2BGRIN1PDK2MTOR | |
| SCHEMBL12137731 | 0.73 | ADORA2A (0.49) | GRIN2BGRIN1ALDH1A1L3MBTL1PARP1 | |
| SCHEMBL28307674 | 0.72 | SCN2A (0.48) | GRIN2BGRIN1ALDH1A1L3MBTL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |