Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM5C | P41229 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.40 |
| ▸ | KDM4B | O94953 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169023 | 0.87 | ALDH1A1 (0.44) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL11347447 | 0.83 | LMNA (0.56) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL17526117 | 0.81 | LMNA (0.44) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL28738078 | 0.81 | KDM4E (0.51) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL20008492 | 0.80 | LMNA (0.43) | LMNASMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL20008477 | 0.76 | MYC (0.46) | LMNASMN1; SMN2NPC1RAB9AKDM5C | |
| SCHEMBL4043325 | 0.76 | LOXL2 (0.49) | KDM5CKDM5BKDM4BMKNK1MKNK2 | |
| SCHEMBL29427234 | 0.76 | LOXL2 (0.49) | KDM5CKDM5BKDM4BMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL28122952 | 0.75 | LOXL2 (0.50) | KDM5CKDM5BKDM4B | |
| SCHEMBL20909893 | 0.74 | UHRF1 (0.43) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5369084-A | Isonicotinic acid derivatives and related spiro compounds with herbicidal action | JANSSEN PHARMACEUTICAL N.V. (BE) | 1994-11-29 | — | — | US | disclosed |
| WO-1992009577-A1 | ISONICOTINIC ACID DERIVATIVES AND RELATED SPIRO COMPOUNDS WITH HERBICIDAL ACTION | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-06-11 | — | — | WO | disclosed |