Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.42 |
| ▸ | ACR | P10323 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 4/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008688 | 0.88 | CPN1 (0.52) | PRSS1ACRCPN1CPB2PARP10 | |
| SCHEMBL20008666 | 0.84 | PRSS1 (0.43) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL1645315 | 0.84 | MAPT (0.51) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL1399029 | 0.83 | KMT2A (0.44) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL9053565 | 0.82 | NR1H4 (0.48) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL9229509 | 0.82 | NR1H4 (0.48) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL7309972 | 0.81 | MAPT (0.47) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL1399027 | 0.80 | PRSS1 (0.43) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL10956570 | 0.79 | KMT2A (0.56) | KMT2APRSS1ACRMEN1SMN1; SMN2 | |
| SCHEMBL20008699 | 0.79 | KMT2A (0.48) | KMT2APRSS1ACRMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | ELYSIUM THERAPEUTICS, INC. | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180085366-A1 | OPIOID COMPOSITIONS RESISTANT TO OVERDOSE AND ABUSE | OPRM1, OPRK1, OPRD1 | KMT2A 1946/4885PRSS1 952/4885ACR 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.