SCHEMBL2001008

SCHEMBL2001008

S=C=NC1CCC(CC2CCC(N=C=S)CC2)CC1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11711679 0.91 APLNR (0.58) APLNR
SCHEMBL289935 0.84
SCHEMBL3903198 0.84 APLNR (1.00) APLNR
SCHEMBL822123 0.82 APLNR (0.47) APLNR
SCHEMBL4751708 0.81 APLNR (0.64) APLNR
SCHEMBL7910521 0.78 APLNR (0.58) APLNR
SCHEMBL10348103 0.76 APLNR (0.56) APLNR
SCHEMBL10348102 0.76 APLNR (0.56) APLNR
SCHEMBL23743495 0.75 ALDH1A1 (0.54) APLNR
SCHEMBL6318341 0.75 ALDH1A1 (0.54) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3743453-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS Novol, Inc. (US) 2020-12-02 EP claimed
US-20200354507-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS NOVOL, INC. 2020-11-12 US claimed
CN-111699207-A Cross-linked optical polymers based on sorbitol 诺韦尔有限公司 2020-09-22 CN claimed
WO-2019147848-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS NOVOL, INC. (US) 2019-08-01 WO claimed
EP-1877839-B1 THERMOSETTING POLY(THIO)URETHANE FORMULATION COMPRISING AT LEAST ONE BLOCK COPOLYMER AND USE THEREOF IN OPTICS FOR THE PRODUCTION OF ORGANIC LENSES HAVING IMPROVED TOUGHNESS ESSILOR INT (FR) 2008-12-03 EP claimed
EP-4431546-A1 SELF-HEALING POLYMER MATERIAL The University of Tokyo (JP) 2024-09-18 EP disclosed
CN-118265743-A Self-healing polymeric material 国立大学法人东京大学 2024-06-28 CN disclosed
WO-2023085303-A1 SELF-HEALING POLYMER MATERIAL 国立大学法人 東京大学 2023-05-19 WO disclosed
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-06-29 US disclosed
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-06-29 US disclosed
EP-3743453-A1 SORBITOL-BASED CROSSLINKED OPTICAL POLYMERS Novol, Inc. (US) 2020-12-02 EP disclosed
US-10844158-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2020-11-24 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5116976-A HINDERED AMINE LIGHT STABILIZER HYDRAZIDES ATOCHEM NORTH AMERICA, INC (US) 1992-05-26 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
US-4631229-A CONTAINING CARBONYL- OR THIOCARBONYLAMINO GROUPS; NONEXUDING OIL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-12-23 US disclosed
US-4559382-A WITH AN ETHYLENICALLY UNSATURATED COMPOUND HAVING CARBONYLAMINO ORTHIOCARBONYLAMINO GROUPS; DIMENSIONAL STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-12-17 US disclosed
EP-0132032-A2 Improved processable radiation curable poly(vinyl chloride) resin compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-01-23 EP disclosed
US-4041208-A ENERGY ABSORBERS, LAMINATED GLASS SHEETS USEFUL AS AUTOMOBILE WINDSHIELDS PPG INDUSTRIES, INC. (US) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10844158-B2 Chain extenders UMPS, PUF60, SMC1A APLNR 2350/4885
US-11046645-B2 Isothiocyanate production method, composition for transporting and storing N-substituted O-substituted thiocarbamate, and isothiocyanate composition TST, SLCO4C1, SLCO2B1 APLNR 4157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.