SCHEMBL822123

SCHEMBL822123

N#CSC1CCC(CC2CCC(N=C=S)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
APLNR P35414 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2001008 0.82 APLNR (0.70) APLNR
SCHEMBL21064654 0.82 KMT2A (0.34)
SCHEMBL17300169 0.80 KMT2A (0.34)
SCHEMBL11711679 0.74 APLNR (0.58) APLNR
SCHEMBL4758528 0.68
SCHEMBL3903198 0.68 APLNR (1.00) APLNR
SCHEMBL289935 0.68
SCHEMBL6578208 0.68
SCHEMBL4751708 0.66 APLNR (0.64) APLNR
SCHEMBL7910521 0.63 APLNR (0.58) APLNR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170267803-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LTD (AU) 2017-09-21 US disclosed
US-20170267803-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LTD (AU) 2017-09-21 US disclosed
EP-3214071-A1 ISOTHIOCYANATE COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2017-09-06 EP disclosed
US-9695268-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2017-07-04 US disclosed
US-9695268-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2017-07-04 US disclosed
EP-1945690-B1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LTD (AU) 2016-07-27 EP disclosed
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-21 US disclosed
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-01-21 US disclosed
US-20150344613-A1 POLYTHIOUREA COMPOSITIONS AND METHODS OF USE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-03 US disclosed
US-20150344613-A1 POLYTHIOUREA COMPOSITIONS AND METHODS OF USE EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-12-03 US disclosed
US-20150105530-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LTD (AU) 2015-04-16 US disclosed
US-20150105530-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LTD (AU) 2015-04-16 US disclosed
US-8962786-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LTD (AU) 2015-02-24 US disclosed
US-8962786-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LTD (AU) 2015-02-24 US disclosed
WO-2014136690-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION 旭化成ケミカルズ株式会社 (JP) 2014-09-12 WO disclosed
US-20110287102-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2011-11-24 US disclosed
US-7964696-B2 Chain extenders POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2011-06-21 US disclosed
US-20090175921-A1 Chain Extenders POLYNOVO BIOMATERIALS PTY LIMITED 2009-07-09 US disclosed
WO-2007033418-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2007-03-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267803-A1 CHAIN EXTENDERS UMPS, PUF60, SMCHD1 APLNR 2409/4885
US-20110287102-A1 CHAIN EXTENDERS UMPS, PUF60, SMCHD1 APLNR 2409/4885
US-20090175921-A1 Chain Extenders UMPS, PUF60, SMC1A APLNR 2350/4885
US-20160016901-A1 ISOTHIOCYANATE PRODUCTION METHOD, COMPOSITION FOR TRANSPORTING AND STORING N-SUBSTITUTED O-SUBSTITUTED THIOCARBAMATE, AND ISOTHIOCYANATE COMPOSITION TST, SLCO4C1, SLCO2B1 APLNR 4157/4885
US-20150344613-A1 POLYTHIOUREA COMPOSITIONS AND METHODS OF USE PNMT, SRM, PUF60 APLNR 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.