Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28186420 | 0.86 | ESR1 (0.32) | — | |
| SCHEMBL27514353 | 0.84 | ESR1 (0.31) | — | |
| SCHEMBL9005285 | 0.83 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL2835240 | 0.83 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL27284604 | 0.83 | LOXL2 (0.35) | KCNH2 | |
| SCHEMBL5815903 | 0.83 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL27861087 | 0.82 | LOXL2 (0.34) | KCNH2 | |
| SCHEMBL5430518 | 0.81 | SLC6A4 (0.41) | — | |
| SCHEMBL6125420 | 0.81 | LPL (0.35) | KCNH2 | |
| SCHEMBL27571893 | 0.81 | KCNH2 (0.30) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104212339-A | Organic silicon gel anti-ice-covering coating as well as preparation method and application thereof | STATE GRID CORP CHINA | 2014-12-17 | — | — | CN | disclosed |
| US-8894985-B2 | Nitric oxide-releasing polymers | AMULET PHARMACEUTICALS, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-7964878-B2 | Light emitting polymer devices using self-assembled monolayer structures | HCF PARTNERS, LP (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110059036-A1 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. | 2011-03-10 | — | — | US | disclosed |
| US-7829553-B2 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | AMULET PHARMACEUTICALS, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20100134052-A1 | Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures | HCF PARTNERS, L.P. (US) | 2010-06-03 | — | — | US | disclosed |
| EP-1968615-A1 | NITRIC OXIDE-RELEASING POLYMERS | Amulet Pharmaceuticals, Inc. (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20070286840-A1 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | AMULET PHARMACEUTICALS, INC. | 2007-12-13 | — | — | US | disclosed |
| US-20070196327-A1 | Nitric oxide releasing polymers | AMULET PHARMACEUTICALS, INC. | 2007-08-23 | — | — | US | disclosed |
| WO-2007067477-A1 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |
| EP-1718316-A2 | NITRIC OXIDE-RELEASING POLYMERS | Amulet Pharmaceuticals, Inc. (US) | 2006-11-08 | — | — | EP | disclosed |
| WO-2006116584-A2 | LIGHT EMITTING POLYMER DEVICES USING SELF-ASSEMBLED MONOLAYER STRUCTURES | DYNAMIC ORGANIC LIGHT, INC. (US) | 2006-11-02 | — | — | WO | disclosed |
| WO-2005081752-A2 | NITRIC OXIDE-RELEASING POLYMERS | AMULET PHARMACEUTICALS, INC. (US) | 2005-09-09 | — | — | WO | disclosed |
| CN-1039996-A | THERMOLABILE HOLE MOULD STENCILS | NITTO DENKO CORP (JP) | 1990-02-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059036-A1 | NITRIC OXIDE-RELEASING POLYMERS | NOS2, NOS3, NOS1 | KCNH2 1404/4885 |
| US-20070286840-A1 | generation of NO from a C-based diazeniumdiolate that is covalently attached to a phenyl-containing polymer( polystyrene homo or copolymer, polyethyene terephthalate, polyamides etc.) without the possibility to form nitrosamines; of vascular stents, vascular grafts, catheters, wound dressings, bandages | NOS3, NOS2, DDT | KCNH2 924/4885 |
| US-20100134052-A1 | Light Emitting Polymer Devices Using Self-Assembled Monolayer Structures | CLTB, CYBA, CLTA | KCNH2 1089/4885 |
| US-20070196327-A1 | Nitric oxide releasing polymers | NOS2, NOS3, NOS1 | KCNH2 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.