SCHEMBL20014045

SCHEMBL20014045

CN(C)c1ccc(C(=O)OC(CS(=O)(=O)O)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 11/20 0.45
▸ HPGD P15428 6/20 0.45
▸ MAPT P10636 6/20 0.45
▸ RAB9A P51151 6/20 0.41
▸ KDM4E B2RXH2 4/20 0.41
▸ NPC1 O15118 4/20 0.41
▸ HSD17B10 Q99714 3/20 0.41
▸ GAA P10253 3/20 0.41
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ TSHR P16473 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ HTT P42858 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ CYP3A4 P08684 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ ALOX15 P16050 1/20 0.37
▸ HDAC3 O15379 1/20 0.37
▸ HDAC4 P56524 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20014047 0.87 MEN1 (0.40) ALDH1A1HPGDMAPTRAB9AKDM4E
SCHEMBL21504706 0.85 EGFR (0.39) L3MBTL1
SCHEMBL20014043 0.83 MLYCD (0.33) ALDH1A1HDAC3HDAC4HDAC1HDAC7
SCHEMBL22694292 0.83 LMNA (0.41) ALDH1A1MAPTRAB9AKDM4ENPC1
SCHEMBL20014046 0.83 ESRRG (0.38) ALDH1A1HPGDMAPTGAAMEN1
SCHEMBL20014049 0.83 EGFR (0.41) ALDH1A1KDM4EGAALMNACYP3A4
SCHEMBL18473354 0.82 USP5 (0.38) ALDH1A1RAB9AKDM4ENPC1SMN1; SMN2
SCHEMBL20013920 0.82 LMNA (0.41) ALDH1A1MAPTRAB9ANPC1GAA
SCHEMBL19756115 0.82 TRPV1 (0.37) MAPTLMNACA2
SCHEMBL13079572 0.81 LMNA (0.44) ALDH1A1MAPTHSD17B10SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10754248-B2 Sulfonium salt, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-08-25 — — US disclosed
US-10180626-B2 Sulfonium salt, resist composition, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-01-15 — — US disclosed
US-20180088464-A1 SULFONIUM SALT, RESIST COMPOSITION, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180088464-A1 SULFONIUM SALT, RESIST COMPOSITION, AND PATTERNING PROCESS LSM14A, PAG1, EWSR1 ALDH1A1 3760/4885HPGD 4073/4885MAPT 2965/4885
US-10180626-B2 Sulfonium salt, resist composition, and patterning process LSM14A, PAG1, EWSR1 ALDH1A1 3760/4885HPGD 4073/4885MAPT 2965/4885
US-10754248-B2 Sulfonium salt, resist composition, and patterning process GPS1, SPIN2B, SPIN1 ALDH1A1 2187/4885HPGD 4462/4885MAPT 2819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback