Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 6/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GLP1R | P43220 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18513360 | 0.90 | MEN1 (0.40) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL24796610 | 0.88 | NOD1 (0.58) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL21389121 | 0.88 | CASP2 (0.53) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL21389124 | 0.86 | CASP2 (0.51) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL22930200 | 0.86 | CASP2 (0.54) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL19155730 | 0.86 | CASP2 (0.54) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL21003636 | 0.85 | CASP2 (0.53) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL27251491 | 0.82 | SIRT1 (0.62) | CASP2NOD1SLC6A5GLP1R | |
| SCHEMBL18929780 | 0.82 | FAAH (0.49) | CASP2FAAHDNM1NAAANOD1 | |
| SCHEMBL24239550 | 0.80 | GLP1R (0.46) | CASP2FAAHNAAANOD1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932580-B2 | Compositions and methods for modulating HBV expression | IONIS PHARMACEUTICALS, INC. (US) | 2018-04-03 | — | — | US | disclosed |