Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 5/20 | 0.57 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 4/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12067617 | 0.88 | TRPM8 (0.70) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL17067000 | 0.85 | CTSV (0.58) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL6988545 | 0.84 | HTR1D (0.78) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL9738676 | 0.81 | CTSV (0.49) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL19186783 | 0.79 | TRPM8 (0.66) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL13931328 | 0.79 | KDM4E (0.54) | MAPTKDM4ELTA4HPLA2G2APOLB | |
| SCHEMBL16491115 | 0.78 | ALDH1A1 (0.56) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL1163168 | 0.78 | HTR1D (0.67) | HTR1DTRPM8MAPTKDM4ELTA4H | |
| SCHEMBL9450864 | 0.77 | CTSV (0.55) | TRPM8MAPTKDM4ELTA4HPLA2G2A | |
| SCHEMBL14488753 | 0.77 | CTSV (0.52) | TRPM8MAPTKDM4ELTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | L'OREAL (FR) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180092822-A1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS | KRT18, TYR, INCENP | HTR1D 455/4885TRPM8 1129/4885MAPT 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.