SCHEMBL200245

SCHEMBL200245

Cc1ccc(S(=O)(=O)NC(CCCCN)C(=O)CCl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 4/20 0.57
MMP9 P14780 2/20 0.57
PLAU P00749 4/20 0.47
HPN P05981 4/20 0.47
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
MMP13 P45452 2/20 0.42
CA1 P00915 2/20 0.42
MMP1 P03956 1/20 0.42
MMP8 P22894 1/20 0.42
CA14 Q9ULX7 1/20 0.42
ALDH1A1 P00352 2/20 0.41
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200247 1.00 MMP2 (0.57) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL920895 0.99 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL11406948 0.99 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
Hydrochloric Acid SCHEMBL15537019 0.98 MMP2 (0.55) MMP2MMP9PLAUHPNITGB3
SCHEMBL1305743 0.89 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
SCHEMBL1305745 0.89 MMP2 (0.56) MMP2MMP9PLAUHPNITGB3
SCHEMBL5490595 0.88 PLAU (0.45) MMP2MMP9PLAUHPNITGB3
SCHEMBL28509074 0.87 MMP2 (0.60) MMP2MMP9PLAUHPNITGB3
SCHEMBL20008635 0.87 MMP9 (0.67) MMP2MMP9ITGB3ITGA2BSLC1A3
SCHEMBL28212986 0.87 MMP9 (0.67) MMP2MMP9ITGB3ITGA2BSLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 430 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2722054-B1 Methods and compositions for oral administration of proteins ORAMED PHARMACEUTICALS INC (IL) 2018-03-21 EP claimed
US-20160206703-A1 METHODS AND COMPOSITIONS FOR ORAL ADMINISTRATION OF PROTEINS ORAMED PHARMACEUTICALS INC. (IL) 2016-07-21 US claimed
US-8333985-B2 Non-glycerol stabilized bone graft WARSAW ORTHOPEDIC, INC. (US) 2012-12-18 US claimed
US-7914542-B2 Devices, systems and methods for treating benign prostatic hyperplasia and other conditions NEOTRACT, INC. (US) 2011-03-29 US claimed
US-20090192439-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2009-07-30 US claimed
US-20090060977-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2009-03-05 US claimed
US-20090018523-A1 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2009-01-15 US claimed
EP-1887976-A2 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS Neotract, Inc. (US) 2008-02-20 EP claimed
US-20070178158-A1 Stabilized bone graft WARSAW ORTHOPEDIC, INC. 2007-08-02 US claimed
US-20060276871-A1 Devices, systems and methods for treating benign prostatic hyperplasia and other conditions EXPLORAMED NC2, INC. (US) 2006-12-07 US claimed
WO-2006127431-A2 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS NEOTRACT, INC. (US) 2006-11-30 WO claimed
US-20060035827-A1 Compositions and methods for the treatment or prevention of gallbladder disease NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2006-02-16 US claimed
US-20030143258-A1 Bone graft WARSAW ORTHOPEDIC, INC. 2003-07-31 US claimed
US-12268797-B2 Non-cultured, partially digested, cryopreserved cartilage product OSIRIS THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-12201283-B2 Devices, systems and methods for treating benign prostatic hyperplasia and other conditions Teleflex Life Sciences Llc (US) 2025-01-21 US disclosed
US-12173348-B2 Method for detecting enzymatic reaction product JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2024-12-24 US disclosed
WO-1993024634-A1 DIPEPTIDYL PEPTIDASE-I, CLONING IT, AND THERAPEUTIC AGENTS CONTAINING INHIBITORS THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-12-09 WO disclosed
US-5252463-A Measuring protease inhibition of a protein THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-10-12 US disclosed
WO-1992000374-A1 PROTEASE CLIPSIN AND METHOD OF USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-09 WO disclosed
US-5069707-A PROTEASE INHIBITOR TO CONTROL HARVESTING TIME AJINOMOTO CO., INC. (JP) 1991-12-03 US disclosed