Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.45 |
| ▸ | HPN | P05981 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200247 | 0.88 | MMP2 (0.57) | PLAUHPNTDP1CA2CA9 | |
| SCHEMBL200245 | 0.88 | MMP2 (0.57) | PLAUHPNTDP1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11406948 | 0.86 | MMP2 (0.56) | PLAUHPNTDP1CA2CA9 | |
| Hydrochloric Acid SCHEMBL920895 | 0.86 | MMP2 (0.56) | PLAUHPNTDP1CA2CA9 | |
| Hydrochloric Acid SCHEMBL15537019 | 0.85 | MMP2 (0.55) | PLAUHPNTDP1CA2CA9 | |
| SCHEMBL29999340 | 0.79 | AIMP2 (0.57) | PLAUHPNTDP1CA2CA9 | |
| SCHEMBL1305745 | 0.77 | MMP2 (0.56) | PLAUHPNTDP1CA2CA9 | |
| SCHEMBL1305743 | 0.77 | MMP2 (0.56) | PLAUHPNTDP1CA2CA9 | |
| Tpck SCHEMBL927265 | 0.76 | MMP9 (0.61) | TDP1CA2MMP2MMP9MMP13 | |
| Tpck SCHEMBL441444 | 0.76 | MMP9 (0.61) | TDP1CA2MMP2MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007519496-A | — | — | 2007-07-19 | — | — | JP | claimed |
| EP-1708651-A1 | STABILIZED BONE GRAFT | Osteotech, Inc., (US) | 2006-10-11 | — | — | EP | claimed |
| WO-2005072656-A1 | STABILIZED BONE GRAFT | OSTEOTECH, INC. (US) | 2005-08-11 | — | — | WO | claimed |