Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 11/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20025356 | 0.86 | METTL3 (0.33) | CHRM2CHRM3METTL3MGLLOPRM1 | |
| SCHEMBL20025020 | 0.83 | MGLL (0.34) | CHRM2CHRM3METTL3MGLLSSTR5 | |
| SCHEMBL28688585 | 0.74 | CHRM2 (0.38) | CHRM2CHRM3METTL3MGLLFFAR1 | |
| SCHEMBL20025375 | 0.74 | CHRM2 (0.36) | CHRM2CHRM3METTL3MGLLFFAR1 | |
| SCHEMBL20024865 | 0.73 | LRRK2 (0.39) | OPRM1OPRL1HCRTR1HCRTR2 | |
| SCHEMBL2142593 | 0.73 | CHRM2 (0.43) | CHRM2CHRM3MGLL | |
| SCHEMBL2139817 | 0.72 | CHRM2 (0.48) | CHRM2CHRM3 | |
| SCHEMBL20024916 | 0.72 | CHRM2 (0.36) | CHRM2CHRM3METTL3MGLLFFAR1 | |
| SCHEMBL20025496 | 0.71 | CHRM2 (0.35) | CHRM2CHRM3MGLL | |
| SCHEMBL20025288 | 0.71 | SIGMAR1 (0.37) | CHRM2CHRM3METTL3OPRM1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059537-A1 | DIAZASPIRO[5.5]UNDECANE DERIVATIVE AND USE THEREOF | 四川海思科制药有限公司 | 2018-04-05 | — | — | WO | disclosed |