Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17859504 | 0.80 | FBP1 (0.44) | AGBL2KDM4ENOTUMFBP1GABRR1 | |
| SCHEMBL3641559 | 0.69 | FBP1 (0.53) | KDM4EFBP1 | |
| SCHEMBL23723955 | 0.65 | AGBL2 (0.45) | GAAAGBL2KDM4ENOTUMGABRR1 | |
| SCHEMBL4675656 | 0.61 | KDM4E (0.51) | GAAAGBL2KDM4EGABRR1 | |
| SCHEMBL29733309 | 0.60 | CYP1A2 (0.46) | AGBL2KDM4EAKR1B1GABRR1 | |
| SCHEMBL11553826 | 0.60 | L3MBTL1 (0.42) | GAAKDM4E | |
| SCHEMBL18359190 | 0.59 | GAA (0.42) | GAAAGBL2KDM4EGABRR1 | |
| SCHEMBL597035 | 0.59 | DDR1 (0.41) | GAAKDM4EDGAT1 | |
| SCHEMBL13765709 | 0.59 | KDM4E (0.57) | GAAAGBL2KDM4EGABRR1 | |
| SCHEMBL8947745 | 0.58 | GABRP (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018059314-A1 | AZABICYCLE DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2018-04-05 | — | — | WO | disclosed |