Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | EGFR | P00533 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20031911 | 0.95 | MAOB (0.41) | MAOBEGFRTHRATHRBHRH3 | |
| SCHEMBL20031909 | 0.90 | MAOB (0.43) | MAOBEGFRHRH3MAPK1PPARD | |
| SCHEMBL20031873 | 0.90 | MAOB (0.38) | MAOBEGFRHRH3PPARDPPARA | |
| SCHEMBL20031890 | 0.90 | MAOB (0.38) | MAOBEGFRHRH3MAPK1MAOA | |
| SCHEMBL20031904 | 0.90 | THRA (0.43) | MAOBEGFRTHRATHRB | |
| SCHEMBL22683257 | 0.89 | MAOB (0.39) | MAOBEGFRHRH3PPARDPPARA | |
| SCHEMBL22703003 | 0.81 | ITGB3 (0.38) | MAOBEGFRPPARDPPARA | |
| SCHEMBL22702989 | 0.80 | THRA (0.47) | MAOBEGFRTHRATHRB | |
| SCHEMBL22683269 | 0.80 | BRD4 (0.52) | MAOBEGFR | |
| SCHEMBL30185375 | 0.80 | BRD4 (0.52) | MAOBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3518746-B1 | [5]HELICENE DERIVATIVES AS MOLECULAR REPORTERS FOR DIAGNOSTIC APPLICATIONS AND METHODS OF SYNTHESIS THEREFOR | NATIONAL SCIENCE AND TECH DEVELOPMENT AGENCY (TH) | 2020-11-25 | — | — | EP | disclosed |
| WO-2018063105-A1 | [5]HELICENE DERIVATIVES AS MOLECULAR REPORTERS FOR DIAGNOSTIC APPLICATIONS AND METHODS OF SYNTHESIS THEREFOR | NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY (TH) | 2018-04-05 | — | — | WO | disclosed |