SCHEMBL2003184

SCHEMBL2003184

Cc1n[nH]c(-c2ccccn2)n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.66
RAB9A P51151 4/20 0.66
SMN1; SMN2 Q16637 4/20 0.66
L3MBTL1 Q9Y468 3/20 0.66
PKM P14618 3/20 0.66
TDP1 Q9NUW8 3/20 0.66
ALPL P05186 2/20 0.66
ALOX15 P16050 2/20 0.66
HSD17B10 Q99714 1/20 0.66
KDM4E B2RXH2 5/20 0.57
BTK Q06187 1/20 0.51
CBFB Q13951 4/20 0.51
METAP1 P53582 4/20 0.51
METAP2 P50579 3/20 0.51
F2 P00734 2/20 0.50
F12 P00748 2/20 0.50
PLAU P00749 1/20 0.50
NOTUM Q6P988 1/20 0.50
LMNA P02545 3/20 0.46
CCR1 P32246 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30030958 1.00 NPC1 (0.66) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL8311588 0.79 SMN1; SMN2 (1.00) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL14041138 0.78 SMN1; SMN2 (0.66) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL21777016 0.78 SMN1; SMN2 (0.66) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL6704225 0.78 SMN1; SMN2 (0.66) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL5789993 0.78 L3MBTL1 (0.66) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL12311986 0.77 NPC1 (0.60) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL2251181 0.77 SMN1; SMN2 (0.60) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL15907865 0.76 CCR1 (0.55) NPC1RAB9ASMN1; SMN2L3MBTL1PKM
SCHEMBL2251038 0.75 NPC1 (1.00) NPC1RAB9ASMN1; SMN2L3MBTL1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376513-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-11-14 US disclosed
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
CN-117242084-A Electrochemical biosensor comprising transition metal complex or redox polymer or sensing membrane for electrochemical biosensor 爱-森新株式会社 2023-12-15 CN disclosed
US-20230357294-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (HK) 2023-11-09 US disclosed
US-20230357294-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS THE UNIVERSITY OF HONG KONG (HK) 2023-11-09 US disclosed
EP-2856528-B1 METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS MERCK PATENT GMBH (DE) 2019-07-03 EP disclosed
EP-2856528-B1 METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS MERCK PATENT GMBH (DE) 2019-07-03 EP disclosed
EP-3046927-B1 POLYCYCLIC PHENYLPYRIDINE IRIDIUM COMPLEXES AND DERIVATIVES THEREOF FOR OLEDS MERCK PATENT GMBH (DE) 2019-01-30 EP disclosed
US-9879177-B2 Metal complexes comprising condensed heteroaromatic rings MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-20120165523-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
EP-1939208-B1 Organometallic complex, and light-emitting element, light-emitting device, and electronic device including the organometallic complex SEMICONDUCTOR ENERGY LAB (JP) 2011-07-20 EP disclosed
US-7960547-B2 Transition metal complexes with carbene ligands and their application Cheng, Chien-Hong (TW) 2011-06-14 US disclosed
US-7960547-B2 Transition metal complexes with carbene ligands and their application Cheng, Chien-Hong (TW) 2011-06-14 US disclosed
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-7807839-B2 Organometallic complex, and light-emitting element and light-emitting device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-10-05 US disclosed
US-20090149653-A1 Transition metal complexes with carbene ligands and their application Cheng, Chien-Hong (TW) 2009-06-11 US disclosed
US-20090149653-A1 Transition metal complexes with carbene ligands and their application Cheng, Chien-Hong (TW) 2009-06-11 US disclosed
EP-1939208-A1 Organometallic complex, and light-emitting element, light-emitting device, and electronic device including the organometallic complex SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-07-02 EP disclosed
WO-2006024997-A1 WHITE LIGHT-EMITTING DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2006-03-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149653-A1 Transition metal complexes with carbene ligands and their application CCRL2, L1CAM, CHI3L2 NPC1 1539/4885RAB9A 1883/4885SMN1; SMN2 4505/4885
US-20230357294-A1 SPIRO-CYCLOMETALATED IRIDIUM EMITTERS FOR OLED APPLICATIONS TALDO1, SRD5A1, SRD5A2 NPC1 580/4885RAB9A 1058/4885SMN1; SMN2 4750/4885
US-20110050093-A1 METHOD OF FORMING METAL COMPLEX COMPOUND, AND ORGANIC ELECTROLUMINESCENCE DEVICE ZFR, PORCN, OR10J3 NPC1 2788/4885RAB9A 2280/4885SMN1; SMN2 3510/4885
US-20120165523-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex CCNE2, CDK2, CDK20 NPC1 4803/4885RAB9A 1325/4885SMN1; SMN2 4729/4885
US-20240376513-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER OXA1L, PDK1, SLC2A3 NPC1 4604/4885RAB9A 3858/4885SMN1; SMN2 4611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.