Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470 | 0.78 | DRD2 (0.47) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL21761445 | 0.78 | ALDH1A1 (0.46) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL15484994 | 0.75 | RARA (0.40) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL5344836 | 0.73 | DRD2 (0.44) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL11387022 | 0.72 | TP53 (0.43) | LMNARARARARBRXRARXRB | |
| SCHEMBL31098228 | 0.71 | DRD2 (0.58) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL5103571 | 0.70 | ALDH1A1 (0.45) | ALDH1A1ALDH1A3HSD17B10 | |
| SCHEMBL1568889 | 0.70 | DRD2 (0.56) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL11505754 | 0.69 | TRPA1 (0.41) | DRD2LMNACHRM2HTR1AADRA2A | |
| SCHEMBL22328978 | 0.69 | RARA (0.35) | DRD2LMNACHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305784-A1 | HAPTENS OF QUETIAPINE FOR USE IN IMMUNOASSAYS | Janssen Pharmaceutica NV (BE) | 2018-04-11 | — | — | EP | disclosed |