SCHEMBL20036422

SCHEMBL20036422

Cc1ccc(-c2cnc(-c3cccc4c3oc3nc(C)ccc34)cc2C)cc1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.35
CRHR1 P34998 1/20 0.34
ENPP1 P22413 2/20 0.33
ENPP3 O14638 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
COMT P21964 1/20 0.31
NPC1 O15118 1/20 0.31
GAA P10253 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
AAK1 Q2M2I8 1/20 0.31
PTPRF P10586 1/20 0.31
PTPN2 P17706 1/20 0.31
PTPN1 P18031 1/20 0.31
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30949393 1.00 ADORA3 (0.35) ADORA3CRHR1ENPP1ENPP3ALDH1A1
SCHEMBL23785417 0.92 KCNA3 (0.37) ADORA3CRHR1ENPP1ENPP3NPC1
SCHEMBL21165413 0.85 ENPP1 (0.33) CRHR1ENPP1ENPP3ALDH1A1HPGD
SCHEMBL31671133 0.84 KCNA3 (0.37) ADORA3CRHR1ENPP1ENPP3NPC1
SCHEMBL25774845 0.84 KCNA3 (0.37) ADORA3CRHR1ENPP1ENPP3NPC1
SCHEMBL15672952 0.83 PRKDC (0.41) CRHR1ENPP3ALDH1A1HPGDNPC1
SCHEMBL20036429 0.83 CRHR1 (0.33) CRHR1AAK1
SCHEMBL20044914 0.82 NPC1 (0.34) ENPP1ENPP3NPC1TGFBR1
SCHEMBL21202791 0.82 CCR1 (0.39) TGFBR1
SCHEMBL20457178 0.82 AAK1 (0.33) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-20220328772-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-13 US disclosed
EP-3858844-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 EP disclosed
US-11011709-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-18 US disclosed
EP-3305796-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-03-31 EP disclosed
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-04-12 US disclosed
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-04-12 US disclosed
EP-3305796-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11011709-B2 Organic electroluminescent materials and devices OCIAD1, RPS8, LMNB1 ADORA3 2585/4885CRHR1 2650/4885ENPP1 3047/4885
US-20220328772-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, RPS8, LSM8 ADORA3 2595/4885CRHR1 2485/4885ENPP1 3154/4885
US-11711968-B2 Organic electroluminescent materials and devices OCIAD1, LMNB1, RPS8 ADORA3 2584/4885CRHR1 2638/4885ENPP1 3045/4885
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 ADORA3 2584/4885CRHR1 2638/4885ENPP1 3045/4885
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 ADORA3 2584/4885CRHR1 2638/4885ENPP1 3045/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.