SCHEMBL20036429

SCHEMBL20036429

Cc1ccc2c(n1)oc1c(-c3cc(C)c(Cl)cn3)cccc12

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 3/20 0.33
ADORA1 P30542 1/20 0.33
MAPT P10636 2/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31671134 0.91 ADORA1 (0.35) CRHR1ADORA1MAPTUSP2POLB
SCHEMBL20036428 0.91 ADORA1 (0.35) CRHR1ADORA1MAPTUSP2POLB
SCHEMBL20457178 0.85 AAK1 (0.33) AAK1
SCHEMBL23785417 0.84 KCNA3 (0.37) CRHR1ADORA1
SCHEMBL20036422 0.83 ADORA3 (0.35) CRHR1AAK1
SCHEMBL30949393 0.83 ADORA3 (0.35) CRHR1AAK1
SCHEMBL31671133 0.82 KCNA3 (0.37) CRHR1ADORA1
SCHEMBL25774845 0.82 KCNA3 (0.37) CRHR1ADORA1
SCHEMBL25761835 0.82 MAOB (0.36) AAK1
SCHEMBL18604409 0.82 CRHR1 (0.34) CRHR1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165040-A Organic electroluminescent material and device 环球展览公司 2024-06-11 CN disclosed
CN-118165039-A Organic electroluminescent material and device 环球展览公司 2024-06-11 CN disclosed
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
US-11711968-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-25 US disclosed
EP-3858844-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 EP disclosed
US-11011709-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-05-18 US disclosed
EP-3305796-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2021-03-31 EP disclosed
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-04-12 US disclosed
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-04-12 US disclosed
EP-3305796-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2018-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11011709-B2 Organic electroluminescent materials and devices OCIAD1, RPS8, LMNB1 CRHR1 2650/4885ADORA1 2173/4885MAPT 3133/4885
US-11711968-B2 Organic electroluminescent materials and devices OCIAD1, LMNB1, RPS8 CRHR1 2638/4885ADORA1 2188/4885MAPT 3147/4885
US-20180102487-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 CRHR1 2638/4885ADORA1 2188/4885MAPT 3147/4885
US-20230309378-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LMNB1, RPS8 CRHR1 2638/4885ADORA1 2188/4885MAPT 3147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.