Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20048287 | 0.90 | KLK7 (0.49) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037101 | 0.86 | KLK7 (0.55) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037202 | 0.86 | KLK7 (0.54) | ALDH1A1HTTMEN1KMT2AMAPT | |
| SCHEMBL20037030 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037237 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037121 | 0.85 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037029 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037149 | 0.82 | LMNA (0.47) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL20037113 | 0.81 | KLK7 (0.70) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL20037082 | 0.79 | KLK7 (0.53) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305781-A1 | CHEMICAL SUBSTANCES WHICH INHIBIT THE ENZYMATIC ACTIVITY OF HUMAN KALLIKREIN-RELATED PEPTIDASE 6 (KLK6) | Deutsches Krebsforschungszentrum (DE) | 2018-04-11 | — | — | EP | disclosed |