Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037557 | 0.82 | LTA4H (0.42) | LTA4HPOLBMEN1KMT2AATM | |
| SCHEMBL20038438 | 0.82 | POLB (0.45) | LTA4HPOLBMEN1KMT2AATM | |
| SCHEMBL20255426 | 0.80 | LMNA (0.53) | MEN1KMT2AATMHRH3ALDH1A1 | |
| SCHEMBL20037892 | 0.80 | ALDH1A1 (0.54) | POLBMEN1KMT2AATMALDH1A1 | |
| SCHEMBL4591964 | 0.79 | HRH3 (0.59) | POLBHRH3ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL20249393 | 0.78 | RET (0.44) | LTA4HPOLBMEN1KMT2AATM | |
| SCHEMBL20037924 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2AATMHRH3ALDH1A1 | |
| SCHEMBL18291437 | 0.77 | ALDH1A1 (0.50) | POLBMEN1KMT2AATMHRH3 | |
| SCHEMBL20037948 | 0.77 | HRH3 (0.43) | MEN1KMT2AATMHRH3ALDH1A1 | |
| SCHEMBL18291020 | 0.76 | CXCR4 (0.51) | MEN1KMT2AHRH3TDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |