Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | FKBP1B | P68106 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19231861 | 0.85 | ALDH1A1 (0.46) | MTORPOLBMEN1KMT2ALMNA | |
| SCHEMBL20038438 | 0.82 | POLB (0.45) | LTA4HATMPOLBMEN1KMT2A | |
| SCHEMBL20038437 | 0.82 | LTA4H (0.42) | LTA4HATMPOLBMEN1KMT2A | |
| SCHEMBL1035345 | 0.80 | ALDH1A1 (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1126048 | 0.80 | ALDH1A1 (0.54) | ATMPOLBMEN1KMT2AGABRP | |
| SCHEMBL19171016 | 0.80 | MEN1 (0.41) | ATMMEN1KMT2AGABRPGABRD | |
| SCHEMBL609436 | 0.80 | LMNA (0.62) | ATMMEN1KMT2ALMNAHRH3 | |
| SCHEMBL1126310 | 0.80 | SIGMAR1 (0.60) | POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL22650374 | 0.79 | ACHE (0.45) | LTA4HMEN1KMT2AGABRPGABRD | |
| SCHEMBL4267512 | 0.79 | ALDH1A1 (0.59) | POLBCHRNB2CHRNA4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305785-A1 | PYRIDO[3,4-d]PYRIMIDINE DERIVATIVE AND PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Teijin Pharma Limited (JP) | 2018-04-11 | — | — | EP | disclosed |