Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941980 | 0.79 | HDAC6 (0.50) | GRM5ACACB | |
| SCHEMBL28655847 | 0.77 | MMP2 (0.34) | — | |
| SCHEMBL1306384 | 0.76 | GABRA1 (0.38) | GRM5APP | |
| SCHEMBL12934323 | 0.75 | HDAC1 (0.38) | — | |
| SCHEMBL1306505 | 0.73 | APP (0.41) | GRM5APP | |
| SCHEMBL8049735 | 0.73 | ALDH1A1 (0.43) | — | |
| SCHEMBL9636621 | 0.72 | HPGD (0.47) | ACACB | |
| SCHEMBL6036758 | 0.72 | RARB (0.55) | ACACB | |
| SCHEMBL7262242 | 0.72 | GABRA1 (0.31) | GRM5 | |
| SCHEMBL168698 | 0.71 | PTPN11 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938599-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL DISEASES | JANSSEN SCIENCES IRELAND UC (IE) | 2018-04-11 | — | — | EP | disclosed |