Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 4/20 | 0.39 |
| ▸ | GAK | O14976 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.37 |
| ▸ | WDR5 | P61964 | 3/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20040479 | 0.79 | MET (0.49) | AOC3METFGFR2FGFR3ACVR1 | |
| SCHEMBL22854288 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL19496746 | 0.76 | AOC3 (0.59) | AOC3 | |
| SCHEMBL13724403 | 0.75 | LRRK2 (0.41) | GAKLRRK2WDR5 | |
| SCHEMBL28265610 | 0.73 | CHI3L1 (0.41) | SLC6A7LRRK2 | |
| SCHEMBL31627720 | 0.73 | CHI3L1 (0.41) | SLC6A7LRRK2 | |
| SCHEMBL28267110 | 0.73 | CHI3L1 (0.41) | SLC6A7LRRK2 | |
| SCHEMBL20606305 | 0.71 | WDR5 (0.38) | GAKLRRK2WDR5 | |
| SCHEMBL20606306 | 0.71 | WDR5 (0.38) | GAKLRRK2WDR5 | |
| SCHEMBL20606546 | 0.71 | WDR5 (0.38) | GAKLRRK2WDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053923-B1 | TRIAZOLOPYRAZINE DERIVATIVES AS TYROSIN KINASE INHIBITORS | KOREA RES INST CHEMICAL TECH (KR) | 2018-04-11 | — | — | EP | disclosed |