Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | FPR2 | P25090 | 6/20 | 0.44 |
| ▸ | PROKR1 | Q8TCW9 | 6/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008128 | 0.70 | NR3C1 (0.54) | ACLYNR3C1PGRMAPT | |
| SCHEMBL7552445 | 0.70 | ACLY (0.35) | ACLYFPR2PROKR1CCR2BCL2 | |
| SCHEMBL2006413 | 0.70 | ACLY (0.44) | ACLYFPR2PROKR1NR3C1PGR | |
| SCHEMBL21930952 | 0.68 | ACLY (1.00) | ACLY | |
| SCHEMBL2009285 | 0.67 | NR3C1 (0.52) | NR3C1PGRTP53MAPT | |
| SCHEMBL2002844 | 0.67 | ERN1 (0.47) | L3MBTL1 | |
| SCHEMBL16508903 | 0.64 | HTR6 (0.46) | ACLYFPR2PROKR1CCR2L3MBTL1 | |
| SCHEMBL24252742 | 0.63 | CYP1A2 (0.51) | MAPT | |
| SCHEMBL30451335 | 0.63 | CYP1A2 (0.51) | MAPT | |
| SCHEMBL6828482 | 0.63 | ACLY (0.48) | ACLYFPR2PROKR1CCR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |