Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.54 |
| ▸ | PGR | P06401 | 6/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006413 | 0.82 | ACLY (0.44) | NR3C1PGRACLYTSHRALDH1A1 | |
| SCHEMBL2004253 | 0.81 | NR3C1 (0.69) | NR3C1PGRACLYNMT1 | |
| SCHEMBL2003953 | 0.76 | NR3C1 (0.44) | NR3C1PGRACLYMCL1TSHR | |
| SCHEMBL2006930 | 0.71 | NR3C1 (0.78) | NR3C1PGRMEN1ALDH1A1KMT2A | |
| SCHEMBL2004063 | 0.70 | ACLY (0.52) | NR3C1PGRACLYMAPT | |
| SCHEMBL2009577 | 0.69 | NR3C1 (0.46) | NR3C1PGRACLYTSHRSMN1; SMN2 | |
| SCHEMBL21930952 | 0.69 | ACLY (1.00) | ACLY | |
| SCHEMBL2004275 | 0.67 | NR3C1 (0.51) | NR3C1PGRTSHRMEN1ALDH1A1 | |
| SCHEMBL2008107 | 0.65 | NR3C1 (1.00) | NR3C1PGRCNR1 | |
| SCHEMBL5234949 | 0.65 | CASR (0.47) | CTSAALDH1A1ACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |