Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.43 |
| ▸ | PGR | P06401 | 6/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003953 | 0.86 | NR3C1 (0.44) | ACLYNR3C1PGRALDH1A1TSHR | |
| SCHEMBL2008128 | 0.82 | NR3C1 (0.54) | ACLYNR3C1PGRALDH1A1TSHR | |
| SCHEMBL2004253 | 0.71 | NR3C1 (0.69) | ACLYNR3C1PGRFPR2PROKR1 | |
| SCHEMBL2004063 | 0.70 | ACLY (0.52) | ACLYNR3C1PGRFPR2PROKR1 | |
| SCHEMBL2005434 | 0.68 | AGPAT2 (0.48) | TSHRPTGDR2AGPAT2 | |
| SCHEMBL2007267 | 0.68 | AGPAT2 (0.48) | TSHRPTGDR2AGPAT2 | |
| SCHEMBL2009577 | 0.67 | NR3C1 (0.46) | ACLYNR3C1PGRTSHR | |
| SCHEMBL2004275 | 0.65 | NR3C1 (0.51) | NR3C1PGRALDH1A1TSHR | |
| SCHEMBL2784654 | 0.63 | AGPAT2 (0.55) | ALDH1A1TSHRPTGDR2AGPAT2 | |
| SCHEMBL2006930 | 0.62 | NR3C1 (0.78) | NR3C1PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |