SCHEMBL20041608

SCHEMBL20041608

CCCCOC(=O)NCc1ccc(C)c(CNC(=O)OCCCC)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.50
TSHR P16473 1/20 0.50
HPGD P15428 4/20 0.49
CYP1A2 P05177 3/20 0.49
CYP2C19 P33261 3/20 0.49
RAB9A P51151 3/20 0.49
NPC1 O15118 2/20 0.49
CYP2C9 P11712 2/20 0.49
FAAH O00519 5/20 0.45
KDM4E B2RXH2 1/20 0.44
CYP3A4 P08684 1/20 0.44
LMNA P02545 1/20 0.44
ACHE P22303 6/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17773305 0.85 SMN1; SMN2 (0.59) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19
SCHEMBL11089953 0.84 RAB9A (0.67) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19
SCHEMBL13387445 0.84 FAAH (0.58) SMN1; SMN2TSHRRAB9ANPC1FAAH
SCHEMBL11089043 0.82 HPGD (0.51) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19
SCHEMBL17766325 0.81 RAB9A (0.52) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19
SCHEMBL14270321 0.80 MMP13 (0.49) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19
SCHEMBL8590341 0.79 CYP1A2 (0.55) SMN1; SMN2TSHRCYP1A2CYP2C19FAAH
SCHEMBL9267385 0.79 ACHE (0.47) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19
SCHEMBL15738567 0.79 FAAH (0.53) FAAHACHE
SCHEMBL17864829 0.78 TSHR (0.50) SMN1; SMN2TSHRHPGDCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037410-B1 METHOD FOR PRODUCING M-XYLYLENE DIISOCYANATE MITSUI CHEMICALS INC (JP) 2018-04-11 EP disclosed