Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443780 | 0.79 | AOC3 (0.63) | AOC3ALDH1A1GAAMAPTADRB2 | |
| SCHEMBL6211895 | 0.79 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1GAAKMT2A | |
| SCHEMBL4705880 | 0.78 | FFAR1 (0.53) | FFAR1AOC3L3MBTL1CA1CA2 | |
| SCHEMBL21988157 | 0.78 | FFAR1 (0.48) | FFAR1L3MBTL1CA1CA2MIF | |
| SCHEMBL4723219 | 0.77 | CNR2 (0.49) | L3MBTL1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL28232253 | 0.75 | FFAR1 (0.51) | FFAR1AOC3L3MBTL1CA1CA2 | |
| SCHEMBL19559551 | 0.74 | TAAR1 (0.36) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL7055084 | 0.72 | MTNR1A (0.54) | ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL6325580 | 0.72 | TAS1R3 (0.44) | CA1CA2ALDH1A1CYP2A6TAS1R3 | |
| SCHEMBL2169972 | 0.72 | L3MBTL1 (0.47) | FFAR1AOC3L3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305763-A1 | DEUTERATED OR ISOTOPICALLY LABELED UREA DERIVATIVES OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF USEFUL AS FPRL-1 AGONISTS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2018-04-11 | — | — | EP | disclosed |