Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31016603 | 0.85 | GPR119 (0.36) | P2RX7GPR119 | |
| SCHEMBL22011297 | 0.78 | PARP1 (0.41) | P2RX7GPR119ESR2 | |
| SCHEMBL30776238 | 0.78 | PARP1 (0.41) | P2RX7GPR119ESR2 | |
| SCHEMBL20042663 | 0.76 | P2RX7 (0.34) | P2RX7ESR1ESR2 | |
| SCHEMBL20042664 | 0.75 | P2RX7 (0.40) | P2RX7ESR1ESR2 | |
| SCHEMBL20042745 | 0.73 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL28380888 | 0.72 | — | — | |
| SCHEMBL20042855 | 0.69 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL19894405 | 0.68 | DPP4 (0.36) | P2RX7 | |
| SCHEMBL19617362 | 0.68 | KMT2A (0.34) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |