Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042660 | 0.79 | CNR1 (0.39) | MEN1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL20042839 | 0.79 | P2RX7 (0.45) | MEN1ALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL20042729 | 0.78 | HSD11B1 (0.43) | LMNATSHR | |
| SCHEMBL20042800 | 0.76 | CNR1 (0.45) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL20042806 | 0.76 | CNR1 (0.47) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL20042816 | 0.76 | CNR1 (0.45) | MEN1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL20042748 | 0.74 | NPC1 (0.49) | ARMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL20042870 | 0.73 | KDM4E (0.35) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL20042776 | 0.73 | P2RX7 (0.41) | MEN1LMNATSHRKMT2A | |
| SCHEMBL20042706 | 0.73 | ALDH1A1 (0.43) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |